Witches and Frogs

Meroë is certainly not the first witch in Classical literature with a penchant for a Baleful Polymorph spell; (Circe, in particular, comes to mind), but she may well be the first witch to turn someone into a frog.  I guess the model of empowered women subverting norms by treating men like they were, literally, less than human stayed an effective one for a long period of time.